OnGuard Immune Defense

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Product Overview

Put Your Immune System OnGuard®

OnGuard® is especially important to people constantly exposed to crowds in planes, trains, schools, theaters, offices, etc. MDR OnGuard combines special extracts of Maitake and Shiitake mushrooms, a fruit called Lo Han, Lotus Seed and Colostrum all combined to support optimal health. Taken on a daily basis the formula can help support healthy immune function and general health and well-being. Its the step beyond multi-vitamins that can keep you in the best of health.

MycoFusion: Providing A Proven Powerhouse of Immune Factors!

Japanese researcher, Dr. Nanba, discovered that a very special extract of Maitake mushrooms provided extraordinary immune-enhancing benefits. Following this discovery, Dr. Nanba created and patented an improved form of his extract and called it MaitakeGold 404, which was found by the University of Louisville to be immune active. This extract was later combined with an organic Shiitake extract, to form OnGuard's key ingredient, MycoFusion™.


Maitake was shown in tests to significantly trigger immune cell activity and phagocytosis, the process whereby harmful pathogens are surrounded and killed. In addition to MycoFusion™, OnGuard also contains other extremely powerful sources of immune support factors praised by several prestigious medical journals.

Fortified with Colostrum. Rich in Antibodies!

Colostrum is the first milk produced by cows to transfer their protective antibodies and immune defenses to their newborn calves. This dairy compound, is rich in numerous antibodies and other immune-support factors. In fact, it is such a potent natural food that Colostrum has been cited in several peer-reviewed medical journals for its effectiveness in supporting immune response for maintaining good health.

Is MDR’s Colostrum Safe?

The Colostrum used in MDR OnGuard® is certified as Grade A pasteurized and collected solely from US dairies that insure the Colostrum is free of:
• Artificial Hormones 
• Antibiotics
• Pesticide
• GMO 
• BSE 

Melon Extract to Help You Feel Your Best!

To further improve OnGuard's effectiveness, the Doctors added Lo Han Kuo, a fruit in the melon family. Millions of Lo Han fruits are consumed each year to restore health, which verifies the safety of this amazing fruit. It is also interesting to note Lo Han Kuo is considered to be a longevity fruit with folklore saying people who eat this fruit often live to be 100 years of age!

Take OnGuard® - and put your immune system ONGUARD!

The biggest advantage of OnGuard is that, unlike Echinacea (a ragweed), it can be taken everyday, for long periods of time - before, during, and after exposure to germs. Supporting your immune system every day with a healthy diet, rest, frequent washing of your hands, and OnGuard is the key to staying healthy. With a 100% money back guarantee you can't afford not to take advantage of this important protective health formula. Try it, and see for yourself how great it is to enjoy robust good health.


Immune-enhancing effects of Maitake (Grifola frondosa) and Shiitake (Lentinula edodes) Mushroom extracts. Vaclav Vetvicka and Jana Vetvickova. Ann Transl Med. 2014 Feb; 2(2): 14.

Product Videos


(11 reviews) Write a Review

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  • 5
    My Most Important Security

    Posted by Linda Zuker on Jun 29th 2020

    Why buy security for everything, when OnGuard offers protection for your most valuable possession - your body.. Since taking OnGuard, my immune system shields me from getting sick all year long. Without good health, everything else you insure will not do what OnGuard can do for you!

  • 5

    Posted by PETER, FL on Jun 29th 2020


  • 5
    OnGuard Immune Formula

    Posted by J. Bruno, NJ on Jun 29th 2020

    I take the Onguard in the winter months to give me the extra boost for my immune system with the MDR Women Tabs. Because I work with small children, I feel I must stay on top of my health. Ive been taking MDR over 15 years and still happy about my decision for using MDR as part of my wellness care. Thanks MDR

  • 5

    Posted by Karen and Bob, GA on Jun 29th 2020

    Onguard does me wonders, especially in the winter time. Having two homes where I eat off one of my property during harvest time and in the winter, I stay fit with my Onguard.

  • 5
    Fantastic product!!

    Posted by B. Foster on Jun 29th 2020

    I have never taken a product like this before and it really works. Feeling great and healthier. Love it!!

  • 5

    Posted by Lilly V. on Jun 29th 2020

    Thanks to MDR!!! Feeling better then ever since taking this wonderful formula!!

  • 5
    Best Health Formula Ever!!!!

    Posted by Tim, CA on Jun 29th 2020

    No doubt this is the best health formula ever. It keeps my immune system strong so I stay healthy. I take one every morning and one capsule before bed. It does not upset my stomach at all. I feel better when I take them. I will NEVER EVER be without OnGuard. Bravo MDR!!!

  • 5
    My favorite MDR product…Better than 5 stars!!! A winner!!!

    Posted by Chris, FL on Jun 29th 2020

    I will never be without OnGuard. It has kept me well year round for the first time in my life and I travel a great deal. I recommend it to all my friends to keep them healthy. This is an outstanding product.

  • 5
    works like magic

    Posted by Harry, KS on Jun 29th 2020

    I use this whenever I feel as though Im getting sick and it kicks whatever cold Im coming down with.

  • 5
    Dont leave home without it!

    Posted by Toby G on Jun 29th 2020

    I love OnGuard.. it is easy to take and I feel protected when I come in contact with so many people! I have not been sick for a very long time... it even helps my sinus! Highly recommend!!!

  • 5
    I fly a lot and cant live without OnGuard!

    Posted by Unknown on Jun 29th 2020

    I fly alot and often end up sitting close to someone who is sick. With my busy lifestyle I cant afford any down time. My stewardess friend told me about OnGuard and how she stays healthy despite all the trips she takes. Wow what a difference OnGuard makes. I am healthy year round! Great product! Thanks MDR.