Put your Immune System “OnGuard” with


Recent research has unveiled that certain food factors can activate immune defenses, helping you stay healthier. But here’s the catch… these turbo-charged, immune-support compounds aren’t always easy to include in your daily diet. That’s why we created OnGuard®.

We wanted to make it easy for you to take a small capsule each day that would shield your health with four clinically-proven compounds that can significantly support your immune system:


#1. Maitake & Shiitake Mushroom Complex

Research has shown that specific fractions isolated from Maitake and Shiitake mushrooms can supercharge your immune defenses. These mushrooms have been celebrated by Naturopathic Doctors, Nutritionists, and medical centers like Memorial Sloan Kettering in New York for their extraordinary immune-enhancing benefits. What sets them apart is their abundance of Beta-Glucans, which are known to be “immune active.” This means they can help support your immune cells, keeping them ready to defend your body.

MDR OnGuard is infused with MaitakeGold 404™, an innovation so groundbreaking that it earned Patent #5,854,404. Over the course of more than 18 years, award-winning author and scientist, Dr. Hiroaki Nanba, PhD, a Biochemist and Immunologist, conducted extensive research in Kyoto, Japan. His dedication led to the discovery of the potent properties within the Maitake mushroom’s fruiting body and Mycelia Biomass. These discoveries have the potential to enhance immune function and stimulate T-cells, which play a crucial role in fortifying your immune defenses against invaders.

This alone would be enough to make OnGuard® a highly effective immune supplement, but MDR added more….

#2. Colostrum: Nature’s Powerhouse of Antibodies

Pure and potent Colostrum is the first milk produced by cows to protect their offspring. It contains over 400 functional active compounds and is rich in protective antibodies and immune factors.

Colostrum has been recognized in hundreds of scientific medical journals for its effectiveness in improving overall wellness. From improving brain focus and energy, bolstering gut and respiratory health, to supporting muscle synthesis, youthful skin and performance, Colostrum is a nutritional treasure to support immune function, cellular repair, and overall good health.

Our Colostrum is Grade A pasteurized, free of antibiotics, and sourced from reputable U.S. dairies, ensuring purity and safety.

Monk Fruit - Lo Han Kuo

#3. Lo Han Melon Extract: Ancient Chinese Widsom for Modern Health

Lo Han Kuo, a Chinese melon extract, has been cherished for centuries for its ability to restore good health and longevity. Ancient writings show it was used to suppress coughs and help respiratory function. It not only tastes delicious but also holds a legacy of promoting well-being.

#4. Sacred Lotus Seed Complex: A Miracle of Nature

UCLA scientists discovered Lotus Seeds capable of blooming after a staggering 1,288 years. These seeds harbor a natural DNA repair enzyme that helps them resist the aging process. Our exclusive patented Lotus Seed extract contains restorative nutrients that support healthy longevity.

We knew that incorporating these immune-active compounds into your daily diet would not be easy. That’s why, with over 40 years of leadership in nutrition, MDR has expertly combined them into one convenient capsule for your benefit. OnGuard is your all-in-one, year-round solution for immune support!

What People Are Saying…


I take it each day and make sure my wife does also. We feel the difference. We take OnGuard daily and will continue to do so for the rest of our lives!

Dr. Andrew Schally

Nobel Prize Laureate & world-renowned Scientist acclaimed for his ground-breaking health discoveries. Author of over 3,000 scientific papers.

I have been taking OnGuard and other MDR formulas every day for over 20 years to stay healthy. It really works! At 89, I am still healthy and raring to go.

Pat Boone

Legendary Singer & Film Star

OnGuard helps keep me healthy as I am constantly traveling and interacting with many people, worldwide.

Nicole Shelley

Model Agency Owner

I feel GREAT! I believe OnGuard was the reason I could knockout whatever I was catching! It helps me stay well and keep going.

"Knockout" Carol Connors

Two-time Academy Award-Nominated Singer/Songwriter who co-wrote "Gonna Fly Now", the theme from "Rocky"

OnGuard has done wonders for my sinuses. I used to start my mornings congested with a stuffy nose but not anymore. Best of all, OnGuard has protected me. In the last 4 years, when my friends were staying home, I was able to jet off on 4 overseas trips for work and even embarked on an African safari vacation without worrying about getting sick. I’ve stayed healthy and vibrant through it all!

Laura Males

Today, a Strong Immune System is Crucial!

But what are you doing to protect your health? With all the viral and bacteria challenges that plague us today, why take a chance? With OnGuard, you go beyond vitamins protecting your health with four immune-active superfoods: MaitakeGold404™, proven by University studies to support immune function; Lo Han fruit, prized for centuries for restoring health; Colostrum, rich in over 400 immune factors; and Lotus Seeds with its DNA repair, age-resistant enzymes.

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Guarantee Seal

OnGuard Works!

You’ll feel better, stay healthier, and enjoy greater well-being. See for yourself. Try it and enjoy our 60-day, money-back guarantee.

Nothing is More Important than Your Health. Protect it with OnGuard!

Order a 30-Day supply and get an additional 30-Days FREE! Plus, get FREE shipping, too!

Try 60 days of OnGuard for just $19.95. Thereafter, you’ll receive a 2-month supply (60 capsules) conveniently shipped fresh to your home bi-monthly for just 39.95 with FREE Shipping! Your Satisfaction is Guaranteed! Cancel or return anytime!

Call MDR Customer Service for more information at:

©2023 MDR Corp – All Rights Reserved   |   14101 NE 4th St, Sunrise, FL, 33325


These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. All testimonials shared are real and verified by customers of our products. Your purchase does not guarantee the same results and any claims made here are an example of what’s possible. You may end up with better, worse, or the same results, depending on your health and other factors. None of the content and products here are a substitute for professional advice from a health care professional, unless otherwise noted.