Youthify your mind and body

Renew Youthful Energy &
Vibrant Good Health
with Super NAD+
 

Don’t settle for aging, when you can recapture that wonderful feeling of youthful good health, with VitalFactors.

Imagine waking up feeling better than you have in years, with energy, great health, and a new zest for life! That’s exactly how many men and women feel after taking VitalFactors. Best of all, you will feel results after just a few days!

  Energy
  Immunity
  Mental Clarity
  Heart Health
  Muscle Tone
  Youthful Skin

★ ★ ★ ★ ★    4.8 average rating from VitalFactors customers

Experience the Daily Effervescent Drink for Healthy Energy & Aging

Over 40 years of nutrition science from MDR.

Get Started Now!

Choose from 3 great options below.

Fast shipping · 90‑day money‑back guarantee

Free Anti-Aging Cream

Start with a 3 month supply of VitalFactors and receive the VitalFactors Anti-Aging Cream – FREE (a $65 value). This gift is yours to keep – even if you return your order for a refund.

♦ Enjoy Younger Looking Skin in Minutes!

♦ Nourish Skin with Rejuvenating Factors

♦ Diminish the Look of Wrinkles

♦ Hydrate and Plump Skin

The Science of Renewal

Aging begins to take its toll when your body’s vital compounds —NAD⁺ and HGH (Human Growth Hormone)— start to decline.
By your 40s, NAD⁺ drops by up to 50%, and HGH by more than 80%. This causes fatigue, slower metabolism, muscle loss, fine lines, and reduced focus.

VitalFactors® helps restore what time takes away.
It replenishes NAD⁺ for energy and DNA repair, and supports your body’s natural HGH production for strength, muscle tone, and youthful skin.

Expect improvements you can see and feel:


⚡ Energy & Vitality

💪 Strength

🧠 Brain Focus

❤️ Heart Health

💇‍♀️ Youthful Skin & Healthy Hair

🔥 Libido & Peak Performance

NADYour Body’s Spark for Life

NAD⁺ (nicotinamide adenine dinucleotide) is found in every cell, powering energy, repair, and renewal.
When NAD⁺ declines, your vitality fades — but restoring it can help reverse those changes.

 

Key Benefits:

⚡ Transforms nutrients into clean cellular energy

🧬 Supports DNA repair & cellular renewal

⏳ Activates longevity enzymes (sirtuins, CD38, PARPs)

💪 Maintains metabolism & immune resilience

❤️ Keeps mitochondria healthy for heart, brain & muscle power

🔋 Reduces fatigue, frailty & muscle loss (sarcopenia)

HGH – A Vital Key to Aging

Human Growth Hormone (HGH) is a natural life sustaining protein that circulates throughout your body, keeping your cells young and vibrant. Unfortunately, as you age, your body secretes less of this vital factor. The decline of Growth Hormone with age is associated with many of the dreaded symptoms of aging.

Dr. Daniel Rudman did a study at the University of Wisconsin with surprising results. He took 26 men between the ages of 61 and 81 and injected them with growth hormone. The men reported remarkable benefits: their body fat decreased. Their youthful muscle tone was restored. Energy and vigor improved. Even skin wrinkles were less evident as skin firmness improved.

Dr. Rudman said that HGH replacement seemed to reverse some aspects of the aging process by 10 to 20 years! The study results are published in the New England Journal of Medicine.

 

Clinical Research Behind the VitalFactors Formula

The  VitalFactors  formula was developed based on over 40 years of clinical research, using scientifically backed ingredients proven to combat the effects of aging and support healthy longevity, youthful vitality and overall well-being.

Click to view the research supporting powerful anti-aging effects of Key ingredients :

Arginine (L-Arginine Hydrochloride)

Benefit : Arginine stimulates the release of growth hormone, enhances circulation, and supports muscle recovery and strength.

Study 1 : Effect of oral administration of arginine on growth hormone secretion (1994),  The Journal of Clinical Endocrinology & Metabolism ,  University of Virginia.

Study 2 : Arginine supplementation boosts HGH release (2005),  Growth Hormone & IGF Research ,  University of Copenhagen.

Study 3 : Arginine infusion triggers growth hormone secretion (2010),  American Journal of Physiology ,  Mayo Clinic.

 

CoQ10 (Coenzyme Q10)

Benefit : CoQ10 supports mitochondrial energy production, improves cardiovascular health, and reduces visible signs of aging.

Study 1 : Coenzyme Q10 enhances mitochondrial function (2018),  The Journal of Nutrition ,  UCLA.

Study 2 : CoQ10 and its skin anti-aging properties (2017),  Journal of Dermatology ,  UCSF.

Study 3 : CoQ10’s role in cardiovascular health (2020),  American Journal of Cardiology ,  University of Texas Health Science Center.

 

Glutamine

Benefit : Glutamine aids in muscle recovery, supports the immune system, and promotes gut health.

Study 1 : Glutamine enhances muscle recovery (2014),  Journal of Gerontology ,  University of Illinois.

Study 2 : Glutamine’s role in immune function and gut health (2011),  American Journal of Clinical Nutrition ,  Tufts University.

Study 3 : Glutamine as a crucial nutrient in aging (2017),  Journal of Clinical Nutrition & Metabolism ,  USC.

 

Grape Seed Extract (OPCs)

Benefit : Grape seed extract protects the skin, supports cardiovascular health, and promotes collagen production.

Study 1 : Grape seed extract improves skin elasticity (2015),  The Journal of Clinical Dermatology ,  Harvard University.

Study 2 : Grape seed extract supports heart health (2013),  Journal of Cardiovascular Pharmacology ,  University of Sydney.

Study 3 : Grape seed extract and collagen production (2019),  Journal of Nutrition and Skin Health ,  University of Bologna.

 

Glycine

Benefit : Glycine helps stimulate growth hormone release, supports collagen production, and enhances sleep and cognitive performance.

Study 1 : Glycine stimulates growth hormone secretion (2003),  Journal of Endocrinology ,  UCSF.

Study 2 : Glycine enhances sleep and cognitive function (2016),  International Journal of Sports Medicine ,  University of São Paulo.

Study 3 : Glycine’s neuroprotective properties (2019),  Journal of Neurochemistry ,  Yale University.

 

Lycopene

Benefit : Lycopene protects the skin from UV damage, promotes heart health, and reduces oxidative stress.

Study 1 : Lycopene’s role in protecting skin from UV damage (2015),  British Journal of Dermatology ,  University of Manchester.

Study 2 : Lycopene supports cardiovascular health (2013),  Journal of Cardiovascular Research ,  Harvard University.

Study 3 : Lycopene reduces oxidative stress (2018),  Journal of Nutritional Biochemistry ,  Stanford University.

 

Magnesium

Benefit : Magnesium is essential for muscle relaxation, sleep quality, and maintaining healthy nerve and muscle function.

Study 1 : Magnesium’s impact on sleep quality and muscle function (2012),  Journal of Sleep Medicine ,  University of Michigan.

Study 2 : Magnesium supports bone and muscle health in aging adults (2015),  Osteoporosis International ,  University of Oxford.

Study 3 : Magnesium’s effect on cognitive health in aging populations (2016),  The Journal of Alzheimer’s Disease ,  UC San Diego.

 

Niacinamide (NAD Profactor)

Benefit : Niacinamide supports energy production, DNA repair, and skin hydration, helping to reverse signs of aging.

Study 1 : NAD’s role in cellular metabolism and aging (2019),  Journal of Clinical Nutrition & Metabolism ,  University of Cambridge.

Study 2 : Niacinamide improves skin hydration and reduces fine lines (2017),  British Journal of Dermatology ,  University of Nottingham.

Study 3 : NAD+ for healthy aging and mitochondrial function (2020),  Nature Reviews Molecular Cell Biology ,  UCL.

 

Potassium

Benefit : Potassium helps maintain fluid balance, supports heart health, and regulates muscle and nerve function.

Study 1 : Potassium’s role in cardiovascular health (2011),  Journal of Clinical Nutrition ,  Johns Hopkins University.

Study 2 : Potassium intake reduces stroke risk (2014),  Stroke Journal ,  UCSF.

Study 3 : Potassium and muscle health in aging adults (2017),  Journal of Clinical Muscle Biology ,  University of Minnesota.

 

Resveratrol (resVida®)

Benefit : Resveratrol promotes longevity, supports heart health, and protects the body from oxidative stress and inflammation.

Study 1 : Resveratrol activates longevity genes and mimics caloric restriction (2009),  Cell Metabolism ,  Harvard University.

Study 2 : Resveratrol’s cardiovascular benefits (2012),  Journal of Clinical Endocrinology ,  University of Barcelona.

Study 3 : Resveratrol improves skin elasticity and reduces wrinkles (2015),  Journal of Dermatology Research ,  University of Michigan.

 

SOD (Superoxide Dismutase) from Extramel® Melon

Benefit : SOD is a potent antioxidant that helps neutralize free radicals, reduce inflammation, and promote youthful skin.

Study 1 : SOD from melon extract reduces oxidative stress (2016),  Journal of Anti-Aging Research ,  University of Bordeaux.

Study 2 : SOD and UV-induced skin aging (2019),  Journal of Dermatological Science ,  University of Florence.

Study 3 : SOD supplementation reduces inflammation in older adults (2017),  Journal of Geriatric Medicine ,  University of Tokyo.

 

Selenium (from Selenomethionine)

Benefit : Selenium supports immune function, thyroid health, and protects cells from oxidative damage.

Study 1 : Selenium’s role in protecting skin and cells (2013),  Journal of Nutrition ,  UC Berkeley.

Study 2 : Selenium supports thyroid function in aging adults (2015),  Journal of Endocrinology ,  Johns Hopkins University.

Study 3 : Selenium supplementation reduces cognitive decline (2017),  American Journal of Clinical Nutrition ,  University of Oxford.

 

Vitamin B12

Benefit : Vitamin B12 boosts energy levels, supports brain function, and helps prevent fatigue by maintaining healthy nerve and blood cells.

Study 1 :  Vitamin B12’s role in cognitive health  (2015),  American Journal of Clinical Nutrition ,  Oxford University.

Study 2 :  B12 and its impact on energy metabolism  (2017),  Journal of Nutrition and Health ,  University of Cambridge.

Study 3 :  Vitamin B12 reduces fatigue and improves nerve health  (2018),  Journal of Gerontology ,  University of Sydney.

 

VitalFactors  provides a comprehensive, scientifically backed approach to help fight signs of aging and extend youthful vitality and good health. The formula can help you regain energy, sharpen mental clarity, improve muscle tone, and rejuvenate your skin. By naturally stimulating your body’s production of  Human Growth Hormone (HGH)  and offering robust antioxidant protection,  VitalFactors  works at the cellular level to help you feel and look younger.

 

A More Natural & Gentle Approach to HGH

Scientific studies have shown that natural Aminopeptides called Secretagogues can coax the body into releasing its own stores of HGH.

VitalFactors uses a proprietary blend of these natural Growth Hormone Releasers combined with other key anti-aging nutrients. Just one or two Effertabs in a glass of water can make a world of difference in how men and women feel.

Five days on and two days off helps your body use the secretagogues in VitalFactors to stimulate your own natural supply of youthifying factors.

Start your journey to a better you today. The youthifying factors in VitalFactors will help you to feel and look younger. You can select a single shipment or automatic delivery, and for the best value, sign up for a 3 month supply to get the lowest pricing and receive a free gift.

Repair, Renew and Rebuild.

Just one or two Effertabs in a glass of water creates a tasty, sparkling drink that releases Youth Factors, Antioxidants, Peptides and Enzymes that help your body to repair, renew, and rebuild.

Feel As Good as You Did Years Ago!

VitalFactors helps revitalize your mind and body with results you can see and feel.

The older you are, the more you will appreciate the benefits of VitalFactors.

How do I take VitalFactors?

Drop one VitalFactors tablet into 8–12 oz of water and let it fully dissolve. It becomes a light, sparkling drink—add ice if you want it cold, then enjoy.

When should I take VitalFactors?

Take VitalFactors in the morning: drop 1 tablet in water, let it dissolve, and drink it before you start your day. Most people use it on their busy 5 days and take 2 days off, but the key is staying consistent.

Who is VitalFactors right for?

VitalFactors is for healthy adults who want steady daily energy, clearer focus, and better stamina. It is not for children, and it’s not intended for anyone who is pregnant, nursing, or with a medical condition without medical guidance. If you’re on medication or have any health concerns, ask your healthcare professional before using VitalFactors.

How will I feel, and how fast does VitalFactors work?

VitalFactors doesn’t act like a high-stimulant energy drink (NO Caffeine), so you shouldn’t feel jittery or “amped.” Most people notice a steady lift in energy and focus the first day, and deeper benefits — more restful sleep, clearer thinking, more consistent daytime energy — improves over 2–4 weeks of daily use.

What are the ingredients in VitalFactors?

VitalFactors contains: Vitamin A (Retinyl Palmitate), Vitamin C (Ascorbic Acid), Vitamin D3 (Cholecalciferol), Vitamin E (d-Alpha Tocopheryl Acetate), Vitamin B1 (Thiamine HCl), Vitamin B2 (Riboflavin), Vitamin B3 (Niacinamide), Vitamin B6 (Pyridoxine HCl), Folic Acid, Vitamin B12 (Methylcobalamin), Calcium (Calcium Carbonate), Magnesium (Magnesium Oxide), Zinc (Zinc Citrate), Potassium (Potassium Bicarbonate), L-Glutamine, L-Arginine (including L-Arginine HCl), Glycine, N-Acetyl L-Cysteine, Nicotinamide Riboside Chloride, L-Glycine Propionyl-L-Carnitine HCl, Grape Skin Extract, Grape Seed Extract, Green Tea Extract (EGCG), Soy Isoflavones, Resveratrol, Fucoidan (Seaweed Polysaccharides), Lotus Seed Extract, Superoxide Dismutase (from melon), and CoQ10.

See research on key VitalFactors ingredients

Arginine (L-Arginine Hydrochloride)

Benefit : Arginine stimulates the release of growth hormone, enhances circulation, and supports muscle recovery and strength.

Study 1 : Effect of oral administration of arginine on growth hormone secretion (1994),  The Journal of Clinical Endocrinology & Metabolism ,  University of Virginia.

Study 2 : Arginine supplementation boosts HGH release (2005),  Growth Hormone & IGF Research ,  University of Copenhagen.

Study 3 : Arginine infusion triggers growth hormone secretion (2010),  American Journal of Physiology ,  Mayo Clinic.

 

CoQ10 (Coenzyme Q10)

Benefit : CoQ10 supports mitochondrial energy production, improves cardiovascular health, and reduces visible signs of aging.

Study 1 : Coenzyme Q10 enhances mitochondrial function (2018),  The Journal of Nutrition ,  UCLA.

Study 2 : CoQ10 and its skin anti-aging properties (2017),  Journal of Dermatology ,  UCSF.

Study 3 : CoQ10’s role in cardiovascular health (2020),  American Journal of Cardiology ,  University of Texas Health Science Center.

 

Glutamine

Benefit : Glutamine aids in muscle recovery, supports the immune system, and promotes gut health.

Study 1 : Glutamine enhances muscle recovery (2014),  Journal of Gerontology ,  University of Illinois.

Study 2 : Glutamine’s role in immune function and gut health (2011),  American Journal of Clinical Nutrition ,  Tufts University.

Study 3 : Glutamine as a crucial nutrient in aging (2017),  Journal of Clinical Nutrition & Metabolism ,  USC.

 

Grape Seed Extract (OPCs)

Benefit : Grape seed extract protects the skin, supports cardiovascular health, and promotes collagen production.

Study 1 : Grape seed extract improves skin elasticity (2015),  The Journal of Clinical Dermatology ,  Harvard University.

Study 2 : Grape seed extract supports heart health (2013),  Journal of Cardiovascular Pharmacology ,  University of Sydney.

Study 3 : Grape seed extract and collagen production (2019),  Journal of Nutrition and Skin Health ,  University of Bologna.

 

Glycine

Benefit : Glycine helps stimulate growth hormone release, supports collagen production, and enhances sleep and cognitive performance.

Study 1 : Glycine stimulates growth hormone secretion (2003),  Journal of Endocrinology ,  UCSF.

Study 2 : Glycine enhances sleep and cognitive function (2016),  International Journal of Sports Medicine ,  University of São Paulo.

Study 3 : Glycine’s neuroprotective properties (2019),  Journal of Neurochemistry ,  Yale University.

 

Lycopene

Benefit : Lycopene protects the skin from UV damage, promotes heart health, and reduces oxidative stress.

Study 1 : Lycopene’s role in protecting skin from UV damage (2015),  British Journal of Dermatology ,  University of Manchester.

Study 2 : Lycopene supports cardiovascular health (2013),  Journal of Cardiovascular Research ,  Harvard University.

Study 3 : Lycopene reduces oxidative stress (2018),  Journal of Nutritional Biochemistry ,  Stanford University.

 

Magnesium

Benefit : Magnesium is essential for muscle relaxation, sleep quality, and maintaining healthy nerve and muscle function.

Study 1 : Magnesium’s impact on sleep quality and muscle function (2012),  Journal of Sleep Medicine ,  University of Michigan.

Study 2 : Magnesium supports bone and muscle health in aging adults (2015),  Osteoporosis International ,  University of Oxford.

Study 3 : Magnesium’s effect on cognitive health in aging populations (2016),  The Journal of Alzheimer’s Disease ,  UC San Diego.

 

Niacinamide (NAD Profactor)

Benefit : Niacinamide supports energy production, DNA repair, and skin hydration, helping to reverse signs of aging.

Study 1 : NAD’s role in cellular metabolism and aging (2019),  Journal of Clinical Nutrition & Metabolism ,  University of Cambridge.

Study 2 : Niacinamide improves skin hydration and reduces fine lines (2017),  British Journal of Dermatology ,  University of Nottingham.

Study 3 : NAD+ for healthy aging and mitochondrial function (2020),  Nature Reviews Molecular Cell Biology ,  UCL.

 

Potassium

Benefit : Potassium helps maintain fluid balance, supports heart health, and regulates muscle and nerve function.

Study 1 : Potassium’s role in cardiovascular health (2011),  Journal of Clinical Nutrition ,  Johns Hopkins University.

Study 2 : Potassium intake reduces stroke risk (2014),  Stroke Journal ,  UCSF.

Study 3 : Potassium and muscle health in aging adults (2017),  Journal of Clinical Muscle Biology ,  University of Minnesota.

 

Resveratrol (resVida®)

Benefit : Resveratrol promotes longevity, supports heart health, and protects the body from oxidative stress and inflammation.

Study 1 : Resveratrol activates longevity genes and mimics caloric restriction (2009),  Cell Metabolism ,  Harvard University.

Study 2 : Resveratrol’s cardiovascular benefits (2012),  Journal of Clinical Endocrinology ,  University of Barcelona.

Study 3 : Resveratrol improves skin elasticity and reduces wrinkles (2015),  Journal of Dermatology Research ,  University of Michigan.

 

SOD (Superoxide Dismutase) from Extramel® Melon

Benefit : SOD is a potent antioxidant that helps neutralize free radicals, reduce inflammation, and promote youthful skin.

Study 1 : SOD from melon extract reduces oxidative stress (2016),  Journal of Anti-Aging Research ,  University of Bordeaux.

Study 2 : SOD and UV-induced skin aging (2019),  Journal of Dermatological Science ,  University of Florence.

Study 3 : SOD supplementation reduces inflammation in older adults (2017),  Journal of Geriatric Medicine ,  University of Tokyo.

 

Selenium (from Selenomethionine)

Benefit : Selenium supports immune function, thyroid health, and protects cells from oxidative damage.

Study 1 : Selenium’s role in protecting skin and cells (2013),  Journal of Nutrition ,  UC Berkeley.

Study 2 : Selenium supports thyroid function in aging adults (2015),  Journal of Endocrinology ,  Johns Hopkins University.

Study 3 : Selenium supplementation reduces cognitive decline (2017),  American Journal of Clinical Nutrition ,  University of Oxford.

 

Vitamin B12

Benefit : Vitamin B12 boosts energy levels, supports brain function, and helps prevent fatigue by maintaining healthy nerve and blood cells.

Study 1 :  Vitamin B12’s role in cognitive health  (2015),  American Journal of Clinical Nutrition ,  Oxford University.

Study 2 :  B12 and its impact on energy metabolism  (2017),  Journal of Nutrition and Health ,  University of Cambridge.

Study 3 :  Vitamin B12 reduces fatigue and improves nerve health  (2018),  Journal of Gerontology ,  University of Sydney.

 

VitalFactors  provides a comprehensive, scientifically backed approach to help fight signs of aging and extend youthful vitality and good health. The formula can help you regain energy, sharpen mental clarity, improve muscle tone, and rejuvenate your skin. By naturally stimulating your body’s production of  Human Growth Hormone (HGH)  and offering robust antioxidant protection,  VitalFactors  works at the cellular level to help you feel and look younger.

See research on key VitalFactors ingredients

MDR stands behind every order with a 90 Day Satisfaction Guarantee and over 40 Years of developing scientifically relevant nutritional formulas.

Join the millions of people who have trusted their health to MDR!

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

All testimonials shared are real and verified as customers of our products. Your purchase does not guarantee the same results and results vary depending on the individual. You have a 90 Day Guarantee of Satisfaction or you may return any product for a refund of the purchase price.

None of the content and products here are a substitute for professional advice from health care professional. Seek your Doctor’s advice for any medical conditions.