OnGuard Immune Defense

Every ingredient, as printed on the label

• Colostrum (from Grade A / US Dairy Pasteurized Milk)
• MycoFusion Mushroom Complex (MaitakeGold 404 (Grifola Frondosa) and Shiitake (Lentinula Edodes) Brown Rice Biomass)
• Lo Han (Momordica Grosevonia) (Fruit)
• Sacred Lotus Seed Complex
• Gelatin
• Magnesium Stearate
• Silicon Dioxide
• Contains: Milk

The actives

Colostrum

First milk from US Grade A pasteurized dairy cows. Naturally rich in immunoglobulins and other immune factors that newborn calves rely on in their first days of life.*

MycoFusion Mushroom Complex

Patented blend of MaitakeGold 404 (Grifola frondosa) and shiitake (Lentinula edodes) on brown-rice biomass. The maitake fraction (US Patent #5,854,404) is rich in beta-glucans associated with immune-cell activation.*

Lo Han (Momordica grosvenorii fruit)

Sweet Chinese melon used for centuries in traditional wellness practice to support overall good health and longevity.*

Sacred Lotus Seed Complex

Patented extract from one of the longest-living seeds known to botany. Supplies protective nutrients and antioxidants studied for their role in healthy aging.*

Other ingredients

Gelatin (capsule), magnesium stearate, silicon dioxide. The Supplement Facts panel is the source of truth on the full list and exact amounts.

Why it’s built this way

OnGuard goes beyond ordinary vitamins. Its heart is MycoFusion™, a patented complex that pairs shiitake with MaitakeGold 404™ — the maitake fraction Dr. Hiroaki Nanba spent years isolating and the University of Louisville confirmed is rich in “immune active” beta-glucans, granted U.S. Patent #5,854,404 because there is genuinely nothing like it. We layer that with colostrum, the antibody-rich first milk a mother cow makes only in the first days of her calf’s life, certified Grade A and collected solely from US dairies free of artificial hormones, antibiotics, and GMO.

Then we reach into traditions thousands of years old. Lo Han, the sweet Chinese melon Eastern healers have prized for centuries to support good health. And sacred lotus seed — the seed UCLA scientists found could still bloom after 1,288 years, supplying protective antioxidants studied for their role in healthy aging. The result is a far wider nutritional footprint than a single-ingredient pill, built for adults who want steady, everyday immune support. Shipped fresh from Sunrise, Florida by MDR, trusted for over 30 years by more than 2 million people.

Selected published research

These studies examine individual ingredients — often at doses and in populations that differ from this product — not the finished formula. They are listed for reference and are not claims about this product.

What verified customers report

5 verified reviews are on file for OnGuard Immune Defense, averaging 5.0 of 5, with 100% rating it five stars. Reviews are collected from verified customers and filtered for compliance; the same set is shown on the product page.

Quality

• Shipped fresh from Sunrise, Florida by MDR
• Colostrum is certified Grade A from US dairies free of artificial hormones, antibiotics, and GMO
• Backed by a 90-day satisfaction guarantee
• MDR is an American company trusted for over 30 years by more than 2 million people