I have never taken a product like this before and it really works. Feeling great and healthier. Love it!!
Product Overview
OnGuard goes beyond ordinary vitamins. Its heart is MycoFusion™, a patented complex that pairs shiitake with MaitakeGold 404™ — the maitake fraction Dr. Hiroaki Nanba spent years isolating and the University of Louisville confirmed is rich in “immune active” beta-glucans, granted U.S. Patent #5,854,404 because there is genuinely nothing like it. We layer that with colostrum, the antibody-rich first milk a mother cow makes only in the first days of her calf’s life, certified Grade A and collected solely from US dairies free of artificial hormones, antibiotics, and GMO.
Then we reach into traditions thousands of years old. Lo Han, the sweet Chinese melon Eastern healers have prized for centuries to support good health. And sacred lotus seed — the seed UCLA scientists found could still bloom after 1,288 years, supplying protective antioxidants studied for their role in healthy aging. The result is a far wider nutritional footprint than a single-ingredient pill, built for adults who want steady, everyday immune support. Shipped fresh from Sunrise, Florida by MDR, trusted for over 30 years by more than 2 million people.
What people say.
Thanks to MDR!!! Feeling better then ever since taking this wonderful formula!!
Onguard does me wonders, especially in the winter time. Having two homes where I eat off one of my property during harvest time and in the winter, I stay fit with my Onguard
The full story
- If you don’t eat right
- Lack sufficient sleep
- Don’t have adequate levels of Vitamin A, D, or Zinc
- Suffer with certain chronic medical issues
- Are over 65 years of age
You Are Under Attack by Germs Daily!
- Lo Han Kuo: Chinese melon extract “Lo Han Kuo” prized for centuries to promote good health and longevity.
- Lotus Seeds: Longest living seeds (1,288 years) revitalize your health. Supplies protective nutrients and antioxidants.
Fortified with Colostrum Rich in Antibodies
Lo Han Melon Used For Centuries

Age-defying Lotus Seeds Boost Your Health!
MDR, a Name You Can Trust
Frequently Asked Questions What’s the recommended use?
Is OnGuard safe to take each day?
*All recommendations are subject to your health care provider’s approval as with any supplement. If I am lactose intolerant can I take OnGuard?
- Most likely yes. OnGuard® contains Colostrum, a natural milk compound which does contain a very small amount of lactose. Most people who are lactose intolerant take OnGuard® with no difficulty. If you are ALLERGIC to milk or mushrooms do not take OnGuard®.
What’s the key to staying healthy?
What’s the Scientific Research?
- Read a study done by the NCBI (National Center for Biotechnology Information) about the effect of mushrooms. Click here to read.
- Read a study done by the NCBI (National Center for Biotechnology Information) about beta glucan. Click here to read.
What are the ingredients?
- Colostrum (from Grade A / U.S. Dairy Pasturized Milk)
- MycoFusion™ Mushroom Complex (MaitakeGold404 (Grifola Frondosa) and Shiitake (Lentinula Edodes) Brown Rice Biomass)
- Lo Han (Momordica Grosevonia) (Fruit)
- Sacred Lotus Seed Complex
- Gelatin
- Magnesium Stearate
- Silicon Dioxide
Shop other MDR products
View all →
VitalFactors – New Breakthrough with Super NAD+
4.9 (65)$149$89

Fitness Tabs Multivitamin for Men
Daily energy multivitamin for men
4.9 (58)$69.95

Fitness Tabs Multivitamin for Women
Daily energy multivitamin for women
4.8 (61)$69.95

VitalFactors Instant Relief Roll-On
Fast cooling muscle relief
5.0 (1)$25.95

VitalFactors Anti-Aging Cream
Firmer, smoother-looking skin
4.5 (2)$65

Active Co-Q10 Ubiquinol
Heart & cellular energy support
5.0 (10)$49.95

Bio H.A. Firm & Flex
Joint comfort & skin hydration
4.9 (7)From $49.95

Chondro-Pro
Cartilage & joint mobility support
5.0 (8)$39.95
Warnings & usage
- Do not exceed the recommended dose. Always follow the directions on the product label.
- If you are pregnant, nursing, taking medication, or managing a medical condition, consult your healthcare professional before use.
- Keep out of reach of children.
- Store in a cool, dry place away from direct sunlight. Do not use if the safety seal is broken or missing.
- Discontinue use and consult a healthcare professional if any adverse reaction occurs.
