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for over 40 years

4.9 after 40 years · over 2 million customers

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4.9/5 · Trusted for over 40 years

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From the people who take MDR

“I have been taking these MDR vitamins for years!”
Faye W., Fitness Tabs for Women
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MDR's headquarters building in Sunrise, Florida

Family-owned
since 1984

MDR stands for Medical Doctors Research. For more than 40 years our family has made formulas that help people stay healthy, active and independent as they age.

  • 40+years of formulas
  • 2M+customers
  • Freeshipping on Subscribe & Save

Real people answer at 1-800-637-8227

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From the people who take MDR

“Fitness and nutrition go hand in hand, which is why I take VitalFactors as my favorite natural energizer.”

Chris CuomoTV journalist, NewsNation · VitalFactors customer

“VitalFactors is part of my training routine. I’ve run the Badwater 135-mile ultramarathon in Death Valley 12 times, and I rely on VitalFactors and other MDR products to stay physically active.”

Frank McKinneyLong-time MDR customer
Nick MurthaOwner of Catalyst Fitness
Dr. Lisa LearnBoard-certified plastic surgeon · paid MDR endorser

“I have taken VitalFactors and other MDR products religiously for over 30 years! When you think I topped the charts before Elvis, and I am still performing, feeling great at 92, you can see why I call VitalFactors my Fountain of Youth!”

Pat BooneLegendary Singer & Film Star · VitalFactors customer

“I use the MDR Fitness Tablets in conjunction with the MDR Stress Release Tabs and have taken them for over 25 years. Excellent products.”

Bill S.Amazon customer

…and more, published word for word since 2012

“Best multivitamin on the market. Morning formula and evening formula.”
Michele N.Fitness Tabs for Men · June 2026
“This is a great formula….i love that the capsule is so small and goes down easily with no after taste. I do feel more flexible and my last physical with the doctor shows i am in great sha…”
LauraPristinium Antarctic Krill · October 2025
“Best product to support the inmunoterapia.”
CARLOS A.OnGuard Immune Defense · April 2025
“Can't say enough on this high-quality product my energy feels grate taking these tab AM/PM is the best? Thank you MDR”
Sonny S.Fitness Tabs for Men · September 2024
“Utilized for years on and off great. You can tell the difference when out of product.”
Amazon CustomerFitness Tabs for Women · September 2024
“Been taking VitalFactors for two months. Love the taste so much that it has become my favorite drink. Hate that I’m supposed to skip 2 days a week but I follow the regimen and am feeling…”
Kara K.VitalFactors · June 2024
“Huge fan of Fitness Tab for Women. My energy has been through the roof and I have never felt better.”
Gabby S.Fitness Tabs for Women · May 2024
“It’s used for overall health. It’s a little on the expensive side.”
Amazon CustomerVitalFactors · February 2024
“I love this and every other MDR product I have ever used. They definitely work and the prices are very reasonable. I can also take them with other products.”
Amazon CustomerFitness Tabs for Women · May 2023
“At age 76, I feel my absolute best when I take Vital Factors. It provides me the energy I need and the mental alertness to accomplish my goals on a daily basis. Also helps me accomplish m…”
Judith H.VitalFactors · December 2022
“Have tried others but always come back to MDR”
M S.Fitness Tabs for Women · December 2022
“I have been taking these vitamins since I was in my 30's. That's a long time ago (not telling how long). I have always enjoyed great health, and I wouldn't change for anything! Please kee…”
Teresa B.Fitness Tabs for Women · December 2022
“THIS PRODUCT IS WAY BETTER THAN ALL MY EXPECTATIONS. IT IS MY FAVORITE SUPPLIMENT. I AM 71. THANK YOU”
JAY M.VitalFactors · November 2022
“I'm 62 years old and have taken many vitamins over the years, but this is the only vitamin I have ever taken that actually makes me feel healthier.”
DavidFitness Tabs for Men · September 2022
“I've been taking/drinking Vital Factors for at least 20 years and never want to stop. The benefits are amazing! Thank you for making such a great vitamin drink.”
Lynn W.VitalFactors · July 2022
“I have been a competitive runner for four decades, so my need for strong supplements to keep me going is exceptional. At one time, I to try a lower priced product that seemed like it was…”
Steve C.Fitness Tabs for Men · June 2022
“These are the best vitamins we have ever taken, Have tried others but always come back to these”
M S.Fitness Tabs for Women · June 2022
“We have more energy and calmness simultaneously. Great bargain and products”
B,C.Fitness Tabs for Men · May 2022
“I have more energy and my vision is clearer. My body does not feel tired.”
B.C.Wild Blueberry & Bilberry Antioxidants · May 2022
“I believe these to be a very good value. At $1.19 per day for vitamins and stress defense for both men and women. Would be even less per day if both parties would be consistent in taking…”
Karen K.Fitness Tabs for Men · March 2022
“I've been taking these supplements for twenty years and they are the best! As MDR provides the latest information with regard to quality ingredients, you can be sure that you're getting j…”
Chris from O.Fitness Tabs for Women · January 2022
“Been using for 15 years. Wouldn’t use anything else”
BruceFitness Tabs for Men · November 2021
“Taking per package instructions… so far so good. The taste is pleasant but hard to describe. I will continue with this system. Thank you”
edward D.VitalFactors · May 2026
“If it works for you like it did for me you’ll find that you sleep better, wake up more refreshed, have more positivity, mental focus and clarity. I’m able to remember more. I even get my…”
Amazon CustomerVitalFactors · July 2025
“Love this, but I wigh it was a little cheaper. My stamina is great, when taken.”
BtrueVitalFactors · March 2025
“MDR vitamins were recommended by a friend and within 1 week I had so much more energy and stamina. Thanks 🙏”
Pamela S.Fitness Tabs for Women · September 2024
“I have been taking these MDR vitamins for years! I feel so good all the time...these are worth the money for sure.”
Faye W.Fitness Tabs for Women · August 2024
“Stress Defense is the best. I’m not sure if they reduce the stress in my life but they certainly give me the energy to deal with everything!”
Kara K.Stress Defense Performance Tabs · June 2024
“I love the energy and brain power I get when I take my Vital Factors ⭐️ I am a senior citizen, and it has revived my energy. I started taking one tablet in the morning but now I take 2🥰a…”
Laura M.VitalFactors · March 2024
“it's an absolute win, after almost 3 years with forced naps during the day, going to bed at 7 or 8 pm and extremely low energy. I purchased it after using some sample that came with my or…”
MirelaVitalFactors · September 2023
“I appreciate the fact you removed titanium dioxide from your formula and added Iodine. I came back to this product because you removed titanium dioxide and iodine is a necessary nutrient.…”
Brian O R.Fitness Tabs for Men · January 2023
“Have tried others but always come back to MDR”
M S.Fitness Tabs for Men · December 2022
“I’m enjoying the vitamins and see the benefit of them”
Chris P.Fitness Tabs for Women · December 2022
“I'm not sure how many people know about MDR since they don't advertise as much, but they are around in vitamin business since 90's as far back as I know. I used to order with PAPER ORDER…”
Kay MFitness Tabs for Women · December 2022
“Taken these’s supplements for years ! Work well for me”
Albert G.Stress Defense Performance Tabs · November 2022
“Been using the Fitness tabs and these for 30+ years. Simply the Best”
M S.Stress Defense Performance Tabs · August 2022
“Best , will make you feel better and think clearer all day .”
Glenn G.Fitness Tabs for Men · July 2022
“it is a vitamin you take 2 times a day, they work fine, if i miss a few days, i feel the difference.”
RONALD E. K.Fitness Tabs for Men · June 2022
“Product easy to use, tablet dissolves easier now, and gives me more energy and focus just after a few days of starting it!”
Happy G.VitalFactors · May 2022
“We have more energy and calmness simultaneously. Great bargain and products”
B,C.Fitness Tabs for Women · May 2022
“I have been taking VitalFactors for several years now and I can say I definitely see and feel the difference! I follow the recommended usage of five days on/two days off and it is working…”
John R.VitalFactors · April 2022
“I believe these to be a very good value. At $1.19 per day for vitamins and stress defense for both men and women. Would be even less per day if both parties would be consistent in taking…”
Karen K.Fitness Tabs for Women · March 2022
“Have been using this supplement for years ! Excellent in theses crazy stressful day’s we are experiencing . Let’s you have a more restful outlook !”
albertgalloStress Defense Performance Tabs · December 2021
“Simply the best! I've been taking the Fitness Tabs for more than 10 years and wouldn't consider any other brand.”
Chris from O.Fitness Tabs for Women · November 2021

Family-owned since 1984

MDR stands for Medical Doctors Research. For more than 40 years our family company in Sunrise, Florida, has helped customers keep their health, vitality and independence as they age.

Physicians, scientists and researchers contribute to our formulas, and we keep them up to date with the latest sound science.

More about MDR
MDR's headquarters building in Sunrise, Florida

Your age‑defying energy drink

VitalFactors is MDR’s effervescent NAD+ formula. Drop two in a glass of water on weekday mornings: energy, focus, and healthy aging in one fizzy ritual.

VitalFactors box beside a glass of water with the effervescent tablets dissolving
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Your Daily AM + PM Nutrition System

The original multivitamin, split into a morning and an afternoon tablet, one formula for men, one for women.

MDR Fitness Tabs for Men AM and PM bottlesMDR Fitness Tabs for Women AM and PM bottles
Shop Men’sShop Women’s

Clinical nutrition,
refined since 1984

Many of our customers have made MDR part of their day for decades.

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