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Woman in a sunlit kitchen sipping a glass of VitalFactors next to the package and a bowl of fresh berries
A simple ritual

Sparkling nutrition you'll actually keep up with.

Drop a tablet into water and let it dissolve into a soft pink sparkling drink. No capsules, no shaker bottle, no extra step in the morning — just a small moment that fits inside the one you already have.

VitalFactors is built around an effervescent format so the hardest part of any wellness routine — being consistent — becomes the easiest part.

What VitalFactors supports

Built for energy, focus, and healthy aging.

  • Active man in a t-shirt on a sunny terrace holding a water bottle and yoga mat

    Cellular Energy

    Supports the cellular energy and stamina your cells rely on.

  • Warm kitchen counter scene with citrus, berries, honey, ginger and a steaming cup

    Antioxidant Defense

    Helps maintain the body's natural defenses against oxidative stress.

  • Man working in a bright home office, writing in a notebook beside a laptop

    Focus

    Supports mental focus and clarity.

  • Man with a towel over his shoulders on a coastal path in warm afternoon light

    Immune & Vascular Wellness

    Supports normal immune function and healthy circulation.

A modern effervescent formula

Beyond a multivitamin.

VitalFactors combines Super NAD⁺, resveratrol, EGCG, and S.O.D. with a foundation of vitamins, minerals, amino acids, enzymes, and botanical antioxidants — formulated to work together in a single effervescent serving.

  • Super NAD⁺Fuels the way your cells turn nutrients into energy.
  • ResveratrolPlant polyphenol that supports healthy aging.
  • EGCGGreen-tea antioxidant for everyday cellular defense.
  • S.O.D.An enzyme that helps neutralize free radicals.
  • Amino acidsBuilding blocks that support muscle and repair.
  • Vitamins & mineralsFoundational nutrients your body runs on daily.
  • EnzymesHelp your body absorb and use what's in the formula.
  • Botanical antioxidantsPlant compounds for broad antioxidant support.

Each ingredient earns its place. Exact amounts are listed on the Supplement Facts panel.

Close-up of a VitalFactors tablet dissolving in a glass of water, releasing a soft pink sparkling drink
How to use

Simple to take.

  1. Drop

    Add 1 to 2 tablets to 8 oz of water.

  2. Dissolve

    Let the tablets dissolve completely.

  3. Drink

    Take 30 minutes before eating, or 2 hours after your last meal.

Use 5 days on, 2 days off. Avoid taking immediately before sleep.

The difference

Why VitalFactors stands out.

Attribute
VitalFactors
Typical capsule supplement
Format
Sparkling effervescent drink
Capsules or tablets
Easy to take
Dissolves in water
Hard to swallow
Active blend
Super NAD⁺, resveratrol, EGCG, S.O.D.
Standard multivitamin
Heritage
Doctor developed since 1984
Generic store brand
Guarantee
90-day money-back guarantee
Often none
Brand format
Premium wellness experience
Generic supplement aisle
  • Doctor developed since 1984
  • 40 effervescent tablets
  • Sugar free
  • Gluten free
  • Vegan formula
  • Caffeine free
  • Contains soy
In their own words

Customer testimonials

Tap to unmute.

Recommended by

Doctors, journalists, and athletes who take it themselves.

  • Chris Cuomo

    Chris Cuomo

    TV journalist · NewsNation primetime anchor

    Fitness and nutrition go hand in hand — that's why I take VitalFactors as my favorite natural energizer.
  • Dr. Lisa Learn

    Dr. Lisa Learn

    Board Certified Plastic & Reconstructive Surgeon

    I take VitalFactors and recommend it to my patients — an easy part of a healthy routine.
  • Pat Boone

    Pat Boone

    Singer & film star · 20+ year user

    VitalFactors has been part of my routine for over 20 years — I wouldn't skip a week.
VitalFactors Supplement Facts panel

Serving size: 2 effervescent tablets · 20 servings per container

  • Super NAD⁺. A coenzyme central to how your cells turn nutrients into ATP — the energy your cells run on.
  • Resveratrol. A polyphenol antioxidant naturally found in red grapes.
  • EGCG (green tea catechin). A botanical antioxidant from green tea.
  • S.O.D. (superoxide dismutase). A naturally occurring antioxidant enzyme.
  • Vitamins, minerals & amino acids. Foundational vitamins (including B-complex and C), trace minerals, and amino acids that round out the formula. Exact amounts on the Supplement Facts panel.*
  • Enzyme & botanical blend. Additional enzymes and botanical antioxidants for broader antioxidant support.*
  • Other ingredients & allergens. Effervescent base (citric acid + sodium bicarbonate), natural flavors. Contains soy. Sugar free, gluten free, lactose free, yeast free, cholesterol free. No animal ingredients.
Questions

Frequently asked.

  • VitalFactors is an effervescent nutritional drink designed to support energy, antioxidant defenses, normal immune function, vascular wellness, and healthy aging. The formula combines Super NAD⁺, resveratrol, EGCG, S.O.D., vitamins, minerals, amino acids, and enzymes. Use it as one part of an overall wellness routine — five days on, two days off, per the label — not as a substitute for a balanced diet, sleep, or medical care.*

  • Drop 1 to 2 tablets into 8 oz of water and stir until fully dissolved, then drink. Take at least 30 minutes before eating or 2 hours after your last meal. The label recommends a 5-on / 2-off cycle — 5 days a week, with 2 rest days. Avoid taking it right before bed.

  • Super NAD⁺, resveratrol, EGCG (green tea catechin), S.O.D. (superoxide dismutase), vitamins (including B-complex and C), trace minerals, amino acids, enzymes, and botanical antioxidants. Exact amounts are listed on the Supplement Facts panel.*

  • VitalFactors contains soy. It is sugar free, gluten free, lactose free, yeast free, and cholesterol free, with no animal ingredients. If you have allergies or other sensitivities, review the full ingredient list on the Supplement Facts panel before starting.

  • No. VitalFactors does not contain caffeine, even though it includes EGCG from green tea (the caffeine has been removed). The full ingredient list is on the Supplement Facts panel.

  • VitalFactors is intended for adult use alongside a normal diet. If you take other supplements or medications — or if you're pregnant, nursing, or managing a medical condition — talk with your healthcare professional before adding anything new to your routine.

  • MDR offers a 90-day satisfaction guarantee. Return any unused portion within 90 days for a refund of the purchase price (less shipping). Customer Service can walk you through the steps.

From customers

What people say.

4.9
★★★★★
65 verified reviews
534
46
30
20
10
★★★★★MDR.com

Been taking VitalFactors for two months. Love the taste so much that it has become my favorite drink. Hate that I’m supposed to skip 2 days a week but I follow the regimen and am feeling amazing.

Kara K.
★★★★★MDR.com

At age 76, I feel my absolute best when I take Vital Factors. It provides me the energy I need and the mental alertness to accomplish my goals on a daily basis. Also helps me accomplish my exercise goals.

Judith H.
★★★★★MDR.com

THIS PRODUCT IS WAY BETTER THAN ALL MY EXPECTATIONS. IT IS MY FAVORITE SUPPLIMENT. I AM 71. THANK YOU

JAY M.
Warnings & usage
  • Do not exceed the recommended dose. Always follow the directions on the product label.
  • If you are pregnant, nursing, taking medication, or managing a medical condition, consult your healthcare professional before use.
  • Keep out of reach of children.
  • Store in a cool, dry place away from direct sunlight. Do not use if the safety seal is broken or missing.
  • Discontinue use and consult a healthcare professional if any adverse reaction occurs.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.