Skip to content

The full story

Renew youthful energy with Super NAD+

VitalFactors is a complete daily wellness formula — vitamins, minerals, amino acids, antioxidants, and botanical compounds — pressed into a single effervescent tablet you drop into a glass of water. One fizzy drink takes the place of the handful of capsules most people swallow before breakfast.*

A VitalFactors effervescent tablet dissolving in a glass of water

Built around Super NAD⁺

NAD⁺ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell, where it helps turn the food you eat into usable energy. The body’s NAD⁺ naturally declines with age — so VitalFactors is built to support your everyday cellular energy with a Super NAD⁺ blend, alongside resveratrol, EGCG, and S.O.D. for antioxidant support.*

Dozens of ingredients, working together

Inside every glass is a 3.5-gram cellular-support blend — Super NAD⁺, resveratrol, EGCG, and S.O.D. — plus a full spectrum of vitamins, minerals, amino acids, enzymes, and plant antioxidants. They’re chosen to support the systems your day runs on: cellular energy and stamina, antioxidant defense against everyday oxidative stress, vascular and immune wellness, and the foundations of healthy skin, hair, nails, and focus.*

VitalFactors effervescent tablet fizzing in a glass of water
VitalFactors box beside a glass of fizzing water with an effervescent tablet splashing in

A rhythm, not a grind

VitalFactors is built around a 5-days-on, 2-days-off cycle — five days on, two days off, the way the formula is designed to be taken. Most people run it Monday through Friday and skip the weekend — your box of 40 effervescent tablets is built around exactly that cadence.

Backed by MDR, leaders in nutrition science since 1984, and a 90-day money-back guarantee.

From customers

What people say.

4.9
★★★★★
35 customer reviews
Read all 35reviews →
531
44
30
20
10
★★★★★MDR.com

Been taking VitalFactors for two months. Love the taste so much that it has become my favorite drink. Hate that I’m supposed to skip 2 days a week but I follow the regimen and am feeling amazing.

Kara K.
★★★★★MDR.com

At age 76, I feel my absolute best when I take Vital Factors. It provides me the energy I need and the mental alertness to accomplish my goals on a daily basis. Also helps me accomplish my exercise goals.

Judith H.
★★★★★MDR.com

THIS PRODUCT IS WAY BETTER THAN ALL MY EXPECTATIONS. IT IS MY FAVORITE SUPPLIMENT. I AM 71. THANK YOU

JAY M.

Product Overview

VitalFactors is a complete daily wellness formula — vitamins, minerals, amino acids, antioxidants, and botanical compounds — pressed into effervescent tablets you drop into a glass of water, two per serving. One fizzy drink takes the place of the handful of capsules most people choke down before breakfast, and it's built to help you show up sharper, steadier, and more like yourself.*

The format is the difference. A VitalFactors tablet dissolves completely in under two minutes, so the actives are already in solution before you take a sip — no capsule shell, nothing to swallow. Effervescents are how Europeans have taken their micronutrients for decades: in water, as a drink.*

Inside every glass is a 3.5-gram cellular-support blend built around Super NAD⁺, resveratrol, EGCG, and S.O.D., alongside a full spectrum of vitamins, minerals, amino acids, enzymes, and plant antioxidants — dozens of ingredients working together rather than one isolated nutrient working alone. They're chosen to support the systems your day actually runs on: cellular energy and stamina, antioxidant defense against everyday oxidative stress, vascular and immune wellness, and the foundations of healthy skin, hair, nails, and focus.*

What most people notice first is steady energy — a clean, even lift that carries through the afternoon instead of spiking and crashing. There's no caffeine and no stimulants in VitalFactors, so it works alongside your morning coffee instead of competing with it, and it won't leave you wired at night.*

VitalFactors is built around a rhythm, not a daily grind. The formula is designed for a 5-days-on, 2-days-off cycle — most people run it Monday through Friday and skip the weekend. Your box of 40 effervescent tablets is built around exactly that cadence.

It comes from MDR — Medical Doctors Research, an American company that has been formulating nutrition since 1984. More than forty years of clinical formulation sit behind every tablet, and the full formula is published right on this page: every ingredient named with its exact per-serving amount, including 300 mg of NMN. It's sugar free, gluten free, lactose free, and yeast free, with no artificial colors and no animal ingredients (it does contain soy).

If you want a more complete wellness routine than a standard multivitamin — and you'd rather reach for a sparkling glass of water than swallow another handful of capsules — VitalFactors is the one weekday glass that earns its place on the counter.*

What’s inside

How much NMN and NADH is in VitalFactors?

VitalFactors contains 300 mg of NMN and 8 mg of NADH per 2-tablet serving.

Per tablet: 150 mg NMN and 4 mg NADH.

NMN (nicotinamide mononucleotide) is an NAD+ precursor. VitalFactors does not contain 300 mg of NAD+ itself.

Sugar free · gluten free · lactose free · yeast free · cholesterol free · no artificial colors · no animal ingredients.

Allergens: Contains soy.

Supplement Facts

Serving size: 2 effervescent tablets · Servings per container: 20 · Calories per serving: 24

  • Vitamin A (as retinyl palmitate)30 mcg RAE2%
  • Vitamin C (as L-ascorbic acid)100 mg111%
  • Vitamin D3 (as cholecalciferol)12.5 mcg (500 IU)63%
  • Vitamin E (as D-alpha-tocopheryl acetate)10 mg67%
  • Thiamin (Vitamin B1)3 mg250%
  • Riboflavin (Vitamin B2)3.4 mg262%
  • Niacin (as niacinamide)24 mg150%
  • Vitamin B6 (as pyridoxine)6 mg353%
  • Folate (as folic acid)200 mcg DFE50%
  • Vitamin B12 (as methylcobalamin)200 mcg8,333%
  • Biotin50 mcg167%
  • Pantothenic acid2 mg40%
  • Calcium (from calcium carbonate)50 mg4%
  • Magnesium (from trimagnesium dicitrate)60 mg14%
  • Selenium (from selenomethionine)20 mcg40%
  • Potassium330 mg7%
  • Sodium274 mg12%

Cellular-support & antioxidant complex

  • L-Glutamine2,000 mg
  • NMN (nicotinamide mononucleotide)300 mg
  • L-Arginine (from L-arginine HCl)200 mg
  • L-Lysine (from L-lysine HCl)200 mg
  • Glycine200 mg
  • Monk fruit extract160 mg
  • Grape skin extract (40% resveratrol)110 mg
  • Grape seed extract (Vitis vinifera, 95% proanthocyanidins)100 mg
  • Green tea extract (EGCG)40 mg
  • Soy isoflavones30 mg
  • Resveratrol (ResVida®)20 mg
  • Laminaria japonica (80% polysaccharides)20 mg
  • Coenzyme Q1010 mg
  • NADH8 mg
  • Superoxide dismutase / catalase (Extramel® melon)6 mg
  • L-Ornithine (from L-ornithine HCl)6 mg
  • Lotus seed extract5 mg
  • Lycopene1 mg

Other ingredients: Citric acid, sodium bicarbonate, potassium bicarbonate, natural flavors (red fruit, berry), steviol glycosides.

Amounts shown per 2-tablet serving. Percent Daily Values are based on a 2,000-calorie diet. Where no %DV is shown, a Daily Value has not been established.

Warnings & usage
  • Do not exceed the recommended dose. Always follow the directions on the product label.
  • If you are pregnant, nursing, taking medication, or managing a medical condition, consult your healthcare professional before use.
  • Keep out of reach of children.
  • Store in a cool, dry place away from direct sunlight. Do not use if the safety seal is broken or missing.
  • Discontinue use and consult a healthcare professional if any adverse reaction occurs.